In recent years，China has faced the pressure of industrial chain outward migration and the risk of industrial chain loss，which has posed challenges to the resilience and safety of industrial chain. In this context，how to accurately understand the industrial chain relationship between China and Southeast Asian countries is very important. This paper decomposes the trade added value between China and ASEAN countries，and argues that the industrial chain relationship between China and Southeast Asian countries is generally a benign interaction. Even to a certain extent，the role of Southeast Asian countries is an international extension of China’s industrial chain system. As a high-profile case，we also focused on the case of Vietnam. On the basis of observing these phenomena，this chapter further analyzes two types of challenges in China’s response to the process of industrial chain migration—economic and non-economic factors，as well as China’s special advantages—the scale of the super-large domestic market and the high return on investment. On this basis，this chapter puts forward policy suggestions from two dimensions：domestic perspective and international perspective.