The background of cargo channel expansion strategy of Beibu Gulf international gateway port is comprehensively analyzed. Combined with the development policy of double circulation of international and domestic economy and building a unified national market formulated by China under the current international situation，as well as the global strategic deployment of China’s future economic and political development，based on the precise positioning of Beibu Gulf International Gateway port in China’s western development and the “Belt and Road” development strategy. The study also seeks to formulate strategies for international cargo passage and domestic cargo expansion of the international gateway port of Beibu Gulf，including long-term and short-term strategies. Based on this，the cargo channel network system of Beibu Gulf international gateway port is constructed，and the expansion strategy of cargo channel of Beibu Gulf International gateway port is further put forward. From the overall guarantee，organization guarantee，policy support，capital support，talent guarantee implementation of security，six aspects have been put forward for the Beibu Gulf international gateway port cargo security measures of channel developing，to push the Beibu Gulf international gateway port to port development upgrade，intensive，internationalization development of Lu Haixin channel port in the west and to bettersupport the western region to participate in international economic cooperation.This would help to move faster to promote land-sea linkages between the Belt and Road Initiative in China.