慢性阻塞性肺疾病(慢阻肺)、过敏性哮喘和支气管哮喘是健康中国2030行动计划防治的重大疾病。2021年,中华医学会《慢性阻塞性肺疾病诊治指南》显示,我国40岁以上人群慢阻肺病患者近1亿人。《全球哮喘防治倡议》、《慢阻肺诊断、治疗与预防全球倡议》等文件均推荐使用吸入制剂进行治疗。本文对哮喘和慢阻肺疾病的治疗策略、市场信息、吸入制剂的定义和分类、国内吸入制剂的发展历程、主要企业的研发申报动态进行了回顾。对产业发展面临的挑战和展望进行了论述。
<<Chronic obstructive pulmonary disease (COPD),allergic asthma and bronchial asthma are major diseases to be prevented by the Healthy China 2030 Action Plan. In 2021,the Chinese Medical Association’s “Guidelines for the Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease” show that there are nearly 100 million people with COPD in China over the age of 40. Documents such as the “Global Initiative for Asthma Prevention” and the “Global Initiative for the Diagnosis,Treatment and Prevention of Chronic Obstructive Pulmonary Diseases” recommend the use of inhalation preparations for treatment. This paper reviews the treatment strategies of asthma and COPD,market information,the definition and classification of inhalation preparations,the development of domestic inhalation preparations,and major companies’ R&D and applications. It also discusses the challenges and prospects facing the industrial development.
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