Character setting is an important link in the creation of sci-fi movies，and it is also the concentrated expression of the creativity of sci-fi movies. Science fiction films respond to the challenges of the post-human era through character setting，showing the director’s foresight of social changes brought about by technological development. The setting of characters such as mutants，cyborgs，and Homo sapiens in Chinese science fiction films embodies the relationship between post-human narrative and bioethics，and expresses the concepts of impartiality，no party，strong roots，and ecological harmony，which are worthy of study.