Due to the continuous impact of the COVID-19，the downward pressure on China’s economy continues to increase，and the development of all walks of life is restricted to a certain extent. Whether the listed companies in Anhui Province can withstand the test of the external environment，their comprehensive development ability has become an important issue of theoretical and practical concern. This report establishes an evaluation index system of comprehensive development capability，and comprehensively analyzes the comprehensive development capability level and ranking changes of Anhui listed companies by using the entropy weight method. The report concludes that a small number of Listed Companies in Anhui perform well，the perform of manufacturing industry is mediocre，and private enterprises need to be strengthened，and puts forward countermeasures and suggestions for listed companies in Anhui Province to expand their own advantages，strengthen their own capacity-building，and promote the development of private enterprises.