It is of great significance to analyze the overall situation of college students’ tourism safety in China under the background of pandemic prevention and control. Based on 18 college students’ tourism safety accidents in 2021，this paper analyzes the overall situation，accident types，accident characteristics and accident causes of college students’ tourism safety in China under the normalized epidemic prevention and control，and puts forward relevant suggestions for the prevention of college students’ tourism safety risks. The results show that in 2021，the overall security situation of college students’ tourism in China is improving，but it is still affected by the pandemic risk，and traditional security risks occur from time to time. Specifically，the types of college students’ tourism safety accidents in 2021 mainly focus on accidents and disasters. In the afternoon and night，tourism safety accidents occur frequently. The spatial distribution of tourism safety accidents involves 13 provinces （autonomous regions）. Tourism places and traffic places are the places with high incidence of accidents. Human factors，environmental factors，facilities factors and management factors are the main causes of college students’ tourism safety accidents. Under the background of the normalization of epidemic prevention and control，the risk prevention of college students’ tourism safety accidents not only needs the comprehensive guarantee of medical treatment，resources，insurance，talents，institutions and other factors，but also needs the coordination and cooperation of universities，tourism authorities，tourism enterprises and college students.