The construction of the prevention and management system of intravenous venous thrombosis in the hospital is a guarantee for effective prevention and diagnosis and treatment of venous thrombosis. Our hospital has achieved remarkable results in the construction of the system，so that the prevention and control system is quickly implemented and the management system is gradually improved. This article introduces the steps and specific processes of the construction of the system，focusing on the analysis of the construction details and methods. It is believed that the construction of the system should be led by the administrative management department and steadily advanced in stages. The means to ensure the standardization of the process，dynamically adjust the quality control indicators，and promote the efficient and stable operation of the project.