The report analyzes the top 100 social medical groups and top 50 listed medical service enterprises in 2021 from the dimensions of number，size，category，geographical distribution，listing and operating status，and understands the development and changes of competitiveness of social medical groups and listed medical service enterprises. hrough the comparative study，it is found that in 2021，the scale of social hospital groups will continue to expand，and ophthalmology and women and children occupy the main advantages in specialty areas. East and North China remain the main centers of social medical group headquarters，with Beijing and Shanghai continuing to top the list，with one new overseas city added. In 2021，the top 50 listed medical service enterprises face fierce competition，the ranking of the list changes greatly，the competitiveness of enterprises is constantly improving，and there is “organic growth”. The social medical industry is about to enter a critical period of transformation from quantitative change to qualitative change. In 2021，the government will strengthen the on-site inspection of listed medical service enterprises and IPO enterprises，and the capital market management will be more strict and standardized. In the future，collectivization development and listing are two major development directions of specialized hospital group.