Based on the “Standards of Information Technology Application Ability for Primary and Secondary School Teachers（Trial）” promulgated by the state，a sample survey was conducted on the teaching ability status of 22，945 teachers in 763 primary and secondary schools in Guangzhou. The results of the survey show that the information technology application ability of primary and secondary school teachers is generally at a moderate level，and there are significant differences among different groups of teachers. The age，education，professional title，professional background，and urban and rural areas of teachers have an extremely significant impact on the ability of primary and secondary school teachers to apply information technology. It is recommended to adhere to standard guidance，build a smart learning support environment，comprehensively consider the development needs of different teacher groups，improve the effectiveness of information-based teaching research and training，and comprehensively improve the information technology application ability of primary and secondary school teachers.