With the continuous upgrade of network technologies and the innovation of mobile terminals，the ways of public entertainment are diversified，and online game has become a significant type of online entertainment. In recent years，online game users have grown rapidly，which includes many teenagers. In order to ensure a healthy online game ecology，government supervision and self-discipline of game enterprises are both necessary. This study summarizes the experience of 37 Interactive Entertainment in online game content governance，including guarding teenagers’ growth，defending users’ privacy，protecting intellectual property rights，pandemic prevention，inheriting Chinese traditional culture and so on，which contributes to the development of the game industry.