Accelerating the opening and development of Nansha Comprehensive Bonded Zone is of great significance to promoting the development of Guangzhou’s open economy，promoting the high-quality development of the Guangdong-Hong Kong-Macao Greater Bay Area and implementing the innovation-driven development strategy. Nansha Comprehensive Bonded Zone has achieved excellent developments：cross-border e-commerce hub base is shaping；vehicle access to the sea is unchoked；its aircraft bonded financial leasing is booming；Asia-pacific engineering plastic distribution center is growing rapidly；international transit collection businesses are agglomerated；the scale of bonded exhibition trading center is broader. Nansha Comprehensive Bonded Zone has become an important platform for port regulatory innovation. Nansha and even Guangzhou need to further play to the policy trial advantages of Nansha Comprehensive Bonded Zone，promote research and planning systematically，innovate regulatory mode，make the new commerce forms stronger and larger，strengthen the linkage of ports，strengthen the construction of hardware and software facilities，upgrade the level of comprehensive service，so as to speed up the high level opening-up and high quality development of Nansha Comprehensive Bonded Zone.