The world is undergoing momentous changes unseen in a century. The new round of technological revolution and industrial transformation is developing in depth. The external environment of the foreign trade has undergone profound and complex changes. On the basis of summarizing the development achievements of Guangzhou’s foreign trade in recent years，this research focused on the new development paradigm featuring dual circulation，in which with the domestic economy and international engagement providing mutual reinforcement，with the domestic market as the mainstay. And it combined with the “14th Five-Year Plan” of business development，high-quality development of foreign trade plans. It is proposed to speed up the innovative development of Guangzhou’s foreign trade，by optimizing international market layout，improving the quality of products，accelerating the development of foreign trade in new forms，to upgrade trade promotion platforms，cultivating the trade of characteristic service and optimizing the business environment，to stimulate new driving force of foreign trade，so as to speed up the overall competitiveness of Guangzhou’s foreign trade.