After the outbreak of COVID-19，the Guangdong Medical Products Administration has made every effort to ensure the supply of medical devices for epidemic prevention and control. Among them，the number of disposable medical masks，New COVID-19 test reagent kits，respirators and infrared thermometer registration certificates ranks first in China，it makes the outstanding contributions to the national and global epidemic. In terms of industrial policy，the Guangdong Medical Products Administration has issued a series of emergency approval policies and detailed guidance documents to optimize work procedures，improve technical review and approval efficiency，give full play to the role of policy navigation，and accelerate market access for epidemic prevention equipment；In terms of supervision，the Guangdong Medical Products Administration strictly controls the quality and safety of medical devices for epidemic prevention and control，improves the supervision means on the marketed medical devices for epidemic prevention and control，and severely crack down on the illegal and criminal acts of medical devices used for epidemic prevention and control，effectively ensuring the use safety of epidemic prevention and control devices. The outbreak of COVID-19 also brings new opportunities and challenges to the medical device industry，such as medical devices for epidemic prevention and control or will be included in the national long-term strategic reserve. Some high-end products will be paid more attention，and all kinds of products will face the survival of the fittest and upgrading iteration. The outbreak of COVID-19 also highlights the problems in the medical device industry，it is urgent to summarize the experience optimization system，formulate the personnel training system，encourage the high-quality development of the medical device industry and improve the industry res.