In 2020，National Medical Products Administration（NMPA）will conscientiously study and implement the major decisions and plans of the Party Central Committee and the State Council，implement the “Regulations on the supervision and administration of medical devices”，take deepening the reform of the review and approval system of medical devices as the main line，and take the “four most stringent” requirements as the fundamental guidance，so as to grasp the epidemic prevention and control and quality supervision on one hand. The results of innovative examination and approval are more remarkable，the pilot of the registrant system continues to deepen，the requirements of “release，management and service” are more actively implemented，and new achievements have been made in the management of medical device registration. This report introduces the reform progress of China’s medical device approval system in 2020.