leisure tourism industry of Macao，affected by the outbreak Covid-19 and the normalized prevention and control of the epidemic，has slumped，and the diversified development of the industry has been seriously hindered. From the perspective of regional cooperation，this paper makes an in-depth analysis of the current situation of Macao’s tourism development in the “post-epidemic” era and the potentials of tourism in the cooperation zone. Under the context of jointly operating the industry，creating good environment，and building a tourism brand of Macao and Hengqin，this paper puts forward to suggestions for accelerating the embedded integration development of the two places in the field of leisure tourism industry.