During the 13th Five-Year，the public health work in Shandong Province has been continuously strengthened，the public health service system covering the entire province residents has been established，the investment of funds has been constantly increased，the scope and coverage of basic public health service projects have been expanded，the strategy of “healthy Shandong” has been deeply implemented，the construction of public health system has been accelerated，and the health level of residents in Shandong Province has been continuously enhanced. In 2020，major strategic achievements of the COVID-19 epidemic prevention and control have been achieved，and a satisfactory Shandong answer has been delivered. However，there are also problems such as the uncertainty of public health security，serious aging in the whole province，short board of emergency prevention and control，shortage of public health personnel，and the rising incidence rate of notifiable infectious diseases. During the 14th Five-Year，Shandong Province should further improve the public health emergency management system，promote the cooperation between medical and preventive measures，provide all-round and full cycle public health and health services，speed up the construction of talent team，improve the public health literacy of residents，and actively respond to the new requirements of the normalization of epidemic prevention and the aging population for the public health undertakings in Shandong Province.