The construction of public cultural service system is an important national cultural development strategy. Guizhou takes the people as the center. And Guizhou Province is based on solving the problems that restrict the construction of the public cultural service system，such as segmentation，dispersion of resources，absence of system，insufficient supply，insufficient innovation and low efficiency and so on. In addition，Guizhou Province also strengthens the top-level design，system guarantee，capital investment，basic guarantee，position construction and facility guarantee，implements the project of benefiting the people，strengthens service guarantee，does a good job in pilot construction，strengthens demonstration guarantee，explores the strategy of public culture promoting rural revitalization and strengthening the guarantee of “intelligence” and “ambition” from the perspective of big culture. So remarkable achievements have been made. These achievements are reflected in the construction of public cultural service system，the initial formation of grass-roots facilities network，the gradual growth of public cultural talents，the increasing supply of public cultural products，more diversified service contents and forms，and wider social participation. In the new era，the high-quality development of public cultural services in Guizhou Province can be carried out around one main line，two grasps and three measures.