2021 is a more difficult year for China’s travel agency industry. The travel agency industry adheres to difficulties and survives in seeking change. The inbound and outbound tourism business has not recovered yet. Although domestic tourism continues to recover，the growth rate of travel agency industry is slowing down，the overall operation effect is poor，the industry losses continue，some traditional travel agencies shut down and hibernate，the staff turnover rate continues to expand，the industry confidence is insufficient，and the survival problems are serious. The pilot work for paying the quality of travel service deposit with insurance，the action plan for strengthening the construction and management of tour guides and the special rectification action of operating travel agencies without permission have created a good environment for the development of travel agencies. Through the exploration of innovation and the perspective analysis of the industry dilemma，this paper puts forward the development direction of the travel agency industry in 2022，explores returning to the true value of service，decentralized business development，pan-centralized business development，paying attention to the in-depth development of micro vacation products and diversified management，etc.