The COVID-19 pandemic has highlighted the vulnerability of human being and exacerbated the disadvantages experienced by persons with disabilities. The measures taken to curb the pandemic and achieve economic and social recovery shall balance the public health interest and individual rights and pay special attention to the high risks of disability communities so as to realize substantive equal protection. China has gained experience in this area in terms of emphasizing and ensuring the right to life and health for persons with disabilities，providing accessible information and service，and enhancing public service in education and employment. During the post-Covid era，it should uphold the principle of equal protection and rights-based sustainable development for persons with disabilities，improve the accessibility and reasonable accommodation mechanisms for their comprehensive participation in social life，and recognized and promote the role of mass organizations and social organizations.