Making every effort to strengthen the innovation engine，create a new highland of independent innovation，and accelerate the transformation of scientific and technological achievements into real productive forces is the main direction of scientific and technological innovation in Pudong New Area in the future. This report finds that Pudong has strong financial guarantee and basic conditions for the transformation of scientific and technological achievements. At present，its scientific and technological innovation achievements have a significant spillover effect on the Yangtze River Delta，However，the absorption effect of external scientific and technological innovation achievements is relatively weak. In view of the above phenomena and problems，on the basis of fully learning from the beneficial experience of the transformation of global scientific and technological innovation achievements，this paper puts forward countermeasures and suggestions to promote the transformation of scientific and technological achievements in Pudong，mainly including：Comprehensively Strengthening the technological innovation ability and achievement transformation carrying capacity of enterprises；Create a platform system for the transformation of scientific and technological achievements at both ends of the link；Promote the formation of high-quality science and technology supply guided by market demand in Colleges and universities；Build a technology transfer talent team with unique Pudong characteristics.