Process of sustained economic growth is a process of industrial transformation and upgrading. Since the beginning of “Twelfth-Five Year Plan”，China has achieved marked progress in industrial transformation and upgrading，which mainly reflects in low-level industries continuing to maintain strong international competitiveness，international competitiveness promotion of median and high-level industry，service industry，and obvious import substitution of low and median products. Although，the above progress has been made，China doesn’t complete the task of adjusting industrial structure，still in the diffcult time of transformation and upgrading of industries. The period of “Thirteenth-Five Year Plan” is a critical to China’s industrial transformation and upgrading. Although the latent opportunity of transformation and upgrading remains high，China faces numbers of challenges，including new changes in the relationship among regions，using both two kinds of advantages and TPP. Faced with such challenges during “Thirteenth-Five Year Plan” period，China，based on the idea of innovation，harmony，green，open，shared，should co-ordinate the international and domestic situation，later and first-move advantages to make new breakthroughs in industrial transformation and upgrading