The healthy development of modern service industry in Yangtze River Economic Belt is a key engine of economic transformation and upgrading，and the modern service industry’s collaborative development between regions is an important driving force to strengthen regional integration，opening up and coordinated development. 2011-2015 The modern service industry of Yangtze River Economic Belt grew faster than the whole country，and the scale of investment was rising；In the sub-sector，financial services，wholesale and retail industry，transportation industry，storage and postal services，real estate and tourism industry showed growth posture；However，regional disparity，and the Competition homogeneity problems still outstanding. 2016 is the first year of “the 13th Five-Year Plan”，and under the background of global economic uncertainty reinforced and the downward pressure of domestic economy，so we should enhance regional cooperation and opening up，and narrow the modern service industry’s disparity between the Yangtze River Economic Belt，and achieve the differentiation professional development.