Small and medium-sized enterprises play an important role on economic stability，structural adjustment，employment promotion and efficiency increase in Sichuan Province. In recent years，small and medium enterprises remained a rapid growth in Sichuan Province，the comprehensive strength has increased greatly. Whereas there is still large gap compared by the developed provinces and cities in China. This article analysized the key point of development of small and medium-sized enterprises in Sichuan Province，and proposed measures from the aspects of government functions transformation，elements security，policy support，and others.