Infrastructure investment from China to ASEAN is an important step to promote China-ASEAN regional economic integration for mutual benefit and win-win result. This paper combines the infrastructure development in ASEAN and the target selection of OFDI from China：Firstly，this paper tries to figure out the internal motivation of infrastructure investment from China to ASEAN，respectively from micro-enterprises’ behavior and macroeconomic operation，using Developing Countries OFDI Theory and Internal and External Macroeconomic Equilibrium Theory. Secondly，it also tries to investigate the feasibility of infrastructure investment from China to ASEAN，from two perspectives of host country and home country，including the infrastructure provision and investment demand potential in ASEAN，the present situation of infrastructure investment from China to ASEAN，and impact factors of advantages or disadvantages as well；Finally，it proposes some countermeasures and suggestions.