The state council puts forward the strategy of Made in China 2025，Guangzhou also puts forward many policies about the intelligent manufacturing. This paper will use Guangzhou as a case to analyze the main influence of intelligent manufacturing on the employment of workers. Firstly，the number of workers decreases because intelligent manufacturing replaces workers with robots. Secondly，it improves the condition of work. Thirdly，it changes the labor market' structure and the labor market becomes polarization. It brings changes to the enterprise too. The cost of management decreases. The mode of management also becomes digitalized and intelligent. At last，the internal labor market develops when companies spend more money on the training system. This paper gives some policy advice according to the investigation. When the government makes relevant policies，it should take the social influence into account. Firstly，it should solve the unemployment problem of workers. Secondly，it should provide workers with more skill training. Thirdly，it should improve the protection for workers' rights. At last，it should standardize new ways of enterprise management.