B& R is a major geopolitical and geo-economy strategy that proposed due to the needs of national security and economic development in the context of the neighboring and international environment tends to be complex. The main path to construct the 21st-Century MSR is：regarding international economic cooperation as the centre，taking the maritime shipping route and infrastructure as main frame，making the key ports，central cities，resource zones and industry districts as support systems，considering connectivity and trade and investment facilitation as a means，and building a community of shared interests and destiny as strategic direction to promote the South China Sea（SCS） and strategic channel-based maritime cooperation and development，achieve the facilitation of maritime connectivity，as well as to promote the economic integration of MSR countries，to construct an open international economic cooperation belt and to build efficient economic corridors. By achieving relations of intertwined interests and mutual benefits with partners，China could reconstruct the new economic cooperation patterns，begin to take part in and even lead the global economic governance，and expand international cooperation and development.