At present，the construction of socialism with Chinese characteristics has entered a new era. The transformation of economic system and national governance system to modernization has provided new opportunities for the development and opening up of the western region with long competitive disadvantage. Based on the analysis of modular networking mechanism，this paper points out that scale expansion and division of labor is a feasible path to achieve independent transformation and upgrading. Agglomeration of large-scale homogeneous and heterogeneous consumption demand is the key to drive module networking. Therefore，the western region should fully docking external environment，to gather to promote transformation，guided by the “transformation-open” synergy principle，driver module network new development mechanism，on the basis of public differences，public governance mechanism to create a hierarchical network structure，the whole process of the development of customized open services，to explore the construction of the whole process of development open a new system. This study is of great practical significance to realize the transformation and development of the inland region of the western region and to promote the transformation and strategic transformation of the country.