The Guangdong-Hong Kong-Macao regional cooperation is a successful model of China’s regional cooperation，as well as a successful model of cross-region and cross-scope-of-law cooperation under the framework of “One Country，Two Systems” and the basic law. With characteristics of “one country，two systems and three scopes of law”，three currencies，and three independent customs territories，the Guangdong-Hong Kong-Macao Greater Bay Area has to learn from the successful experience of the bay areas in other countries，and take into consideration its actual conditions while the convergence of rules is analyzed. To explore cross-region and cross-scope-of-law convergence of rules in Qianhai，deepening reform and opening up，the construction of the Guangdong-Hong Kong-Macao Greater Bay Area，the national dual-cycle strategy of international and domestic markets，and Qianhai’s positioning and reality should all be taken into consideration. To be specific，efforts should be made to draw on successful experience，strengthen industrial exchanges，lower the threshold，deepen the development of pilot projects，optimize the allocation of resources，and directly link up with international rules.