CSSD（central sterile supply department） is the key department of nosocomial infection management. It undertakes the cleaning，disinfection，sterilization and supply of all reused medical instruments and articles. Strengthening the construction and management of CSSD and ensuring the quality of sterile articles are of great significance to effectively reduce hospital infection，ensure medical safety and patient safety. The CSSD Information System is a tool for hospital CSSD to realize process quality management. Through quality control and data analysis of quality standards，operating procedures，result confirmation of each node in the workflow，it is clear who？（Who does） When？（When does it do it？） Where？What？（What do you do？） In order to achieve the quality control and traceability of each link in the process of disposal of sterilized articles.