Based on the field investigation and literature analysis，this paper fully grasps the basic situation of Guangdong’s key industrial chains，such as electronic information industry，high-end equipment manufacturing industry，smart home appliances and materials，deeply analyzes the main problems existing in upgrading Guangdong’s industrial chain supply chain modernization level，and puts forward some policy suggestions for upgrading Guangdong’s industrial chain supply chain modernization level，developing modern industrial system and promoting economic system optimization and upgrading during the 14th Five-Year Plan period.