Firstly，this report analyzed the basic development of the Guangdong-Hong Kong-Macao Greater Bay Area and the industrial chain innovation chain of 11 cities in terms of the overall industrial layout，the basic advantages，the spatial layout，and the basic situation of key industrial chains；Secondly，it sorted out the policy system of the 11 cities in the Guangdong-Hong Kong-Macao Greater Bay Area to promote the development of the industrial chain and innovation chain，and analyzed of the “chain length system” policy implemented by each city in the process of promoting the development of the industrial chain and the innovation chain，and this paper also introduced the specific policy content of the 11 cities from the aspects of finance，the land，the finance and the talents. Finally，this paper put forward some policy suggestions to promote the industrial chain innovation chain for the Guangdong-Hong Kong-Macao Greater Bay Area.