To achieve carbon peaking by 2030 and carbon neutrality by 2060 is key national policy for China to deal with climate change. Mitigation and adaptation are complementary strategies to address climate change. In the context of carbon neutrality，climate change adaptation remains important and indispensable，especially critical when link with synergies between mitigation and adaptation. This paper identified the climate-related risks at globally and in China under 1.5℃ and 2.0℃ warming；summarized the concept，evolution and relationship of mitigation and adaptation synergies；listed research and practice of mitigation and adaptation synergy in urban planning，energy，infrastructure sectors. On this basis，the proposed suggestion for climate change adaptation included：（1）Improving working mechanism and strengthen long-term coordination；（2）Pushing frontiers of knowledge of climate change risks and adopting a systematic response；（3）Developing sector-based multi-level technical guidance and establish a user-friendly platform for climate change risk assessment and adaptation；（4）promoting research and practice on synergies between adaptation and mitigation.