As one of the eight pilot free trade zones（FTZ）along the Yangtze River Economic Belt，the Yunnan Pilot Free Trade Zone represents a key link connecting the Yangtze River Economic Belt with the South Asia and Southeast Asia region covered by the “Belt and Road Initiative”. The Yunnan FTZ boasts significant geographical advantages. In light of the new era and the new development stage，the Yunnan Pilot Free Trade Zone needs to boldly blaze a trail towards institutional innovations and experiments based on rules，regulations，management and standards so as to contribute “Yunnan Wisdom” to the development the Pilot Free Trade Zones across China.