In 2020，in the face of the sudden COVID-19，human resources and social security departments at all levels remained at the top of the “six priorities” where stability is the key and the “six areas” where protections are needed. The coverage of China’s on-job injury insurance system has continued to expand，the fund size has further increased，and the burden of enterprise contributions has been reduced. In terms of system reform practices，more attention is being paid to expanding the coverage of the system，providing protection for health care workers in the context of prevention and control of the COVID-19 to enhance the resilience of the system，and improving the medical coverage of work-related injury insurance and further reducing the rates. In terms of system reform trends，China should accelerate the establishment of a multi-level work injury protection system，improve the management service mechanism，and actively explore the synergistic management mechanism with medical insurance and the occupational injury protection mechanism for employees in the new economy and new industry.