The Pearl River Delta urban agglomeration，as the leading area of reform and opening up，is one of the regions with the most dynamic economic development and the earliest urban construction in China. This report describes the formation and development process of the Pearl River Delta urban agglomeration，and the development status of urban healthy life. On this basis，it evaluates and analyzes the urban healthy life of the Pearl River Delta urban agglomeration from the five dimensions of economic security，public service，environmental health，cultural health and medical health. The conclusions of this report are helpful to understand the current situation，advantages and disadvantages of healthy life construction in the Pearl River Delta urban agglomeration，and provide guidance and reference for the further development of the urban agglomeration and the healthy life of urban residents.