The Yangtze River Delta economic circle has unique development advantages and plays an important role in the historical process of China’s expanding opening up and building a community of shared future for mankind. This part constructs the index system including economic security，public service，environmental health，cultural health and medical health，evaluates the urban healthy life of the Yangtze River Delta urban agglomeration，helps to analyze the current situation of urban healthy development of the Yangtze River Delta urban agglomeration，and points out the direction for the coordinated development in the future.