This study analyzes the regional distribution characteristics of China’s marathon from the four economic regions，provincial administrative units，urban agglomerations，and prefecture level cities. The results show that：on the whole，the regional distribution of China’s marathon is in line with the level of economic development，and has formed a echelon pattern，and the eastern coastal areas，especially the Yangtze River Delta，are active in marathon；The central and western regions hold the upper and middle marathon events，but there are many highlights and key areas，especially in Hubei，Sichuan，Hebei and Yunnan provinces，as well as Chengdu Chongqing，the middle reaches of the Yangtze River and the central Yunnan Urban Agglomeration；The activity of marathon in Northeast China，Tianjin，Xinjiang and Tibet is low；The regional distribution of Marathon in China shows a high degree of agglomeration，and the degree of regional development imbalance is high. Therefore，this study puts forward suggestions for the regional layout and development of China’s marathon：consolidate the key gathering areas of Marathon development；Strengthen the important highlight area of Marathon development；Support marathon to develop relatively low-lying areas.