Novel coronavirus pneumonia is a high-risk population. The number of cruise ships is large，and it is highly crowded. It is relatively closed. Once infected people boarded the cruise ship，the risk of new crown pneumonia spread is high. Moreover，the crew on the cruise ship come from different countries，and the cruise ship will travel to different overseas ports. If there is an epidemic，it will cause huge losses and international impact. As the largest and busiest Wusongkou international cruise port in Asia，in the traditional peak season of cruise tourism in the Spring Festival，in the face of sudden outbreaks，with a high sense of responsibility and sensitivity，we started source control in advance，strictly implemented port investigation，and took the lead in formulating joint prevention and control work plans for port joint inspection units，cruise ports，cruise companies，travel agencies and relevant government departments in China，The first to formulate novel coronavirus pneumonia emergency response process，take the lead in making clear the scope and standard of close contact with the cruise tourists，and discourage and prevent tourists from coming to the key epidemic areas，distinguish tourists from key areas and non key areas，and implement the measures of entry-exit diversion，and make early start，early prevention and control，and early isolation. In January 20，2020，the novel coronavirus pneumonia was imported into class B infectious diseases by Wei Jian，and the first class control and prevention measures were adopted. The last cruise liner arrived in January 29th，and 10 voyages，42 thousand and 700 arrivals and 21 thousand and 800 crew members were obtained.