The paper introduces the classification of digital twin applications，and the positive significance of promoting the transformation development of manufacturing industry chain from automation to digitalization and intelligentization. It focuses on the application and digital solutions of digital twin technology in the planning，design，and production process of autobody. With the goal of digital management in autobody line life cycle，the project divides the autobody line into three stages，such as prophase planning and design，production and delivery and the maintenance services as well. With the technical foundation of 5G，industrial internet and AI，the project provides the solutions to adapt to the need of different stages of digital planning，digital twin of autobody line process and the building of intelligent manufacturing service platform. It can effectively improve production efficiency，reduce production cost，and shorten the transformation and implementation period of autobody line. It mainly introduces the digital solutions of different scenarios，such as virtual and real 3D scanning reconstruction scheme for planning and design，5G+VR authentication scheme，virtual debugging of autobody line with the working condition of all elements scheme，and intelligent manufacturing service platform for production operations，piping quality monitoring system and 5G+digital twin. It also analyses the key elements of digital twin lightweight modeling and implementation path，realizes the industrial energization and application promotion of 5G+digital twin technology in automobile，engineering machinery，semiconductor，rail transportation and other industries. It is beneficial to build the new forms of digital solutions based on 5G+digital twin which conform to the requirements of the national “Made in China 2025” development planning and has a large market space and application prospect.