From the perspective of multi-source big data，this report presents the overall situation and regional differences of the integration and development of culture and tourism in China. From the comprehensive index of cultural and tourism integration industry，it covers 6 secondary indicators，12 tertiary indicators and 42 fourth-level indicators. Beijing and Shanghai are in the forefront of the development of cultural and tourism integration，while Wuhan，Chengdu and Xian have also achieved better integration of cultural and tourism industries. From the sub-indicators，the weights of cultural and tourism resources integration index，cultural tourism integration industry index，cultural tourism information integration index，cultural tourism integration influence index，times integration index and cultural tourism industry development elasticity index account for 0.1348，0.2859，0.1756，0.2520，0.1287 and 0.0229 respectively. It can be seen from the report that there are great differences in the integration of cultural tourism industry among regions，and there is little difference in the anti-risk ability of cultural tourism industry development. From the perspective of regional differences，the comprehensive development level of cultural and tourism integration industry in the eastern region is the strongest，followed by the central and western regions，and the development level in the northeast region is weak.