The right to informed consent is the basic right of subjects in drug clinical trials. In recent years，researchers do not fully fulfill the obligation of disclosure，and cases infringing on the subject’s right to informed consent occur frequently，but there are few successful cases in litigation，indicating that there are loopholes in China’s existing laws and regulations，which is difficult to truly and effectively protect the subject’s right to know and independent decision-making. Through the retrieval and analysis of the existing cases of drug clinical trials on the case website，after sorting out such cases，this paper summarizes the chaos that infringes on the subject’s right to informed consent in practice，and puts forward rectification suggestions on this basis.