Speeding up the construction of a new development pattern with the domestic big cycle as the main body and the domestic and international double cycle promoting each other is a major strategic deployment after China has entered a new stage of development. China’s CBD，with its outstanding advantages in scientific and technological innovation，has become a “bridgehead” to support the “double circulation” development. It has gained a number of important experiences in strengthening the ability of independent scientific and technological innovation，improving the level of science and technology service industry，building a highland for scientific and technological talents，optimizing the business development environment of enterprises，and widely carrying out international exchanges and cooperation. At the same time，in the “fourteenth five year plan” and longer period in the future，the improvement of CBD’s scientific and technological innovation ability still faces a series of challenges. It is urgent to further explore and innovate in deepening the reform of system and mechanism，breaking through the bottleneck of innovation chain，strengthening the construction of talent team，improving the government’s governance ability，and enhancing the innovation radiation level，so as to promote high-quality “double circulation” development.