Under the development concept of “great protection，great opening，and high quality”，breaking through the shackles of the ecological environment and realizing sustainable and high-quality development have become the top priority of Shaanxi’s economic and social development in the new era. In order to analyze the coordination between ecological protection and high-quality economic development in Shaanxi，the entropy TOPSIS method was used to comprehensively score the level of ecological protection and high-quality economic development in Shaanxi，and a calculation model for coupling coordination degree was constructed to identify the evolution characteristics of the coupling coordination degree. The degree of coupling coordination between ecological protection and high-quality economic development in Shaanxi has surpassed the low-level antagonistic stage and the primary coordination stage，and has entered the intermediate coordination stage in an all-round way. Shaanxi should accelerate the conversion of new and old kinetic energy，realize the integrated development of production，life and ecological environmental protection，and achieve high-quality development under the limitations of the ecological environment.