General Secretary Xi Jinping attended the 40th anniversary celebration of the establishment of the Shenzhen Special Economic Zone and emphasized that “innovation must be the first driving force and win the initiative in the global technological revolution and industrial transformation”. Relying on innovation-driven connotative growth，Shenzhen has taken the lead in setting out a high-quality development path in Shenzhen，and has rapidly emerged as an international and innovative city full of charm，power，vitality，and innovation，creating a miracle in the history of world development. Through a comprehensive summary of Shenzhen’s practice and exploration of innovation-driven development，this paper puts forward suggested countermeasures to adapt to the new development stage，implement new development concepts，and integrate into the new development pattern，further highlighting the powerful leading role of innovation and providing the national model for high-quality development. with strong and motivated support.