The COVID-19 Pandemic was spreading all over the world in 2020，which has a significant impact on the public safety of Chinese enterprises and citizens’ production and life overseas. In the next 2-3 years，the world is likely to be under the “post-pandemic situation”. How to ensure the safety of the medical and health industry chain becomes a serious problem that every country needs to think about. This report examines the status of China’s medical and health industry chain，the supply and demand changes of key medical products under the impact of the pandemic，and vaccine distribution. The main findings of this report are that the prevention and control of the COVID-19 mainly depends on the the supply of personal protection products，and China has performed well in this regard. However，in developed countries，especially in the United States，many measures are unfavorable，and the supply of personal protection products for pandemic prevention and control relies heavily on overseas production，which directly promotes the restructuring of the supply chain of the medical and health industry. It is worth noting that before the outbreak of COVID-19，the United States highly relied on China in personal protective equipment，which aggravated the US accusation against China. In 2021，countries are focusing on the production and distribution of vaccines. However，major manufacturers underestimate the difficulties in accelerating vaccine production in the short term，resulting in lower supply than expected. In addition，“vaccine nationalism” also increases the difficulty of vaccine distribution in various countries. If we attempt to end the pandemic as soon as possible，then the cooperation of all countries is very important. In fact，the benefits of cooperation are far greater than beggar-my-neighbor policy.