Distribution plays a key rolein Medical Device life cycle，and its quality management is critical to the quality of product delivered to end user. However，limiting to medical device distribution characteristicse.g. product variety，complexity of business model，decentralized distribution channel and localized Health Authority supervision，the quality management of medical device distribution isnot so professional as manufacturing. With the reinforcement of medical device post-market surveillance led by China government in recent years，the capacity of quality management has become an important booster for the development of medical device distributing enterprises and essential core competitiveness. This paper aims to share quality management experiences of medical device distribution based on years of practice as a marketing company.