Objective：to study the industrial chain layout and future development trend of the domestic A-share listed companies of medical equipment and provide some reference materials for the industry research. Methods：teased out the domestic A-share listed companies of medical device and summarized the characteristics of the industrial chain layout of medical device companies by case study. Results：the industrial chain layout of each listed medical device company has its own basic characteristics，which are closely related to its subdivision area. For example，high-value consumables focus on R & D and distribution in related disease areas，while the companies of domestic medical device lay particular emphasis on distribution in online business. Conclusion：the industry will present a trend of continuous concentration and cross-border mergers and acquisitions will become normal with the development of domestic medical equipment companies. This development is also in the general direction of the state industrial policy.