Since the beginning of this century，with the introduction of the Four-Most-Stringent requirements for food safety and the implementation of national food safety strategies，China’s food safety regulatory reforms and innovations and their effects Significant progress and achievements have been made in this regard. With the background of coordinating epidemic prevention and control and food safety，the 2020 food safety regulatory reform and innovation will be achieved in terms of activating the sense of responsibility and implementing the main responsibility of the enterprise，the innovation of the ‘Internet+ supervision’ mechanism，and the ‘better integration of effective markets and promising governments’. Looking to the future，the reform and innovation of food safety supervision need to further combine ‘strictness’ and ‘modernization of governance’ to promote high-level food safety governance.