Huaihai Economic Zone，as one of the earliest inter-provincial economic cooperation organizations in China，has experienced the period of 20 member cities’ horizontal joint development，the period of 8 member cities’ integration construction and the period of 10 member cities’ coordinated development. At present，The Huaihai Economic Zone is in the critical period of comprehensively deepening coordinated development. It has encountered the opportunity of transformation development speed-up and overall high-quality development. The regions collaborate with each other for continuous development in diversified fields and vast space.