The construction of the new generation information infrastructure in Guangdong-Hong Kong-Macao Greater Bay Area has been vigorously promoted and developed rapidly. The information and communication technology facilities in the region have been improved，and the inter-city interconnection broadband has been expanded. Some cities have taken the lead in entering the 5G era，and the construction of data centers is in the ascendant. The new generation of information infrastructure has been innovated and applied in the fields of science，education，production and life，and the “wisdom plus” infrastructure system has been initially constructed.